A hospital in the north-western Idlib province of Syria supported by Medecins Sans Frontieres (MSF) has been destroyed in a Russian air strike.

The facility in Maarat al-Numan was struck by four rockets in the early hours of Monday morning, and at least eight staff members are currently missing.

The independent non-partisan medical charity did not say who bombed the facility, but one monitoring group reported that the rockets came from Russian aircraft, who have been active in the skies over Idlib in recent days.

The incident comes days after world powers, including Russia, agreed to a limited cessation of hostilities in Syria in order to let aid reach those most in need.

The five year conflict in Syria has cost more than 250,000 lives and forced 11 million people to flee their homes.

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